TECHNOZYM® VWF:Ag ELISA

Antigenic determination of von Willebrand factor in plasma and plasma concentrates using 2 polyclonal antibodies.
Classification of Von Willebrand disease type 1, 2 or 3 is possible using the VWF : CBA ELISA kit. (Specialized hemostasis)

- Better reproducibility.
- Better sensitivity.
- Better correlation with high molecular weight (HPM) forms of VWF.
- Better sensitivity in detecting low amounts of VWF in severe type 1 deficiency.

VWF is a multimeric high molecular weight (HPM) glycoprotein involved in primary hemostasis.
VWF protects FVIII from degradation and transports it to plasma, and mediates platelet activation by binding to their membrane receptors GPIb and GPIIb / IIIa.
A quantitative or qualitative defect of VWF causes hemorrhagic pathologies which can be acquired or hereditary. VWF assay is needed to determine the type of disease.