CRYOcheck™ Clot S™
| CCS-15 | Kit | 2 x 5 x 1.5 mL | 150 tests |
| CCS-30 | Kit | 2 x 5 x 3.0 mL | 300 tests |
Determination of functional protein S in citrated human plasma by coagulant method.
Description of the CRYOcheck™ Clot S™
The CRYOcheck™Clot S™ kit allows the determination of functional protein S by chronometric method in human plasma.
Advantages
- Unaffected by high FVIII levels: 600%
- No interference with heparins: 1.2 IU / mL
- No additional dilutions
- No waste
- Suitable for large series
- No reconstitution
- Easy identification
- Vials suitable for hemostasis analyzers
Informations
Protein S is a vitamin K dependent protein. It is a physiological inhibitor of coagulation.
It acts as a cofactor of activated protein C by promoting the inactivation of FVa and FVIIIa, prothrombin, of the prothrombinase complex, FX.
A protein S deficiency can be either acquired (hepatocellular insufficiency, vitamin K deficiency, anti-protein S antibody, ...) or constitutional (heterozygous or homozygous deficiency) grouped into 2 types depending on whether the deficiency is quantitative (type I) or qualitative (type II).
