Factor VIII Deficient Plasma Native
Freeze-dried
Packaging options
| 4-5154007 | Vial | 5 x 1.0 mL | 100 tests |
| 4-5154016 | Vial | 50 x 1.0 mL | 1 000 tests |
Plasma deficient for the determination of Factor VIII.
Description of the Factor VIII Deficient Plasma Native
Native Factor VIII Deficient Plasma is made from a pool of plasmas from hemophiliac A donors, native (congenital deficiency), lyophilized, having a coagulant activity <1% for FVIII.
All other coagulation factors have normal values. VWF level is normal.
Informations
Factor VIII is a glycoprotein mainly synthesized by the liver.
It circulates in the plasma in the form bound to VWF which protects it from rapid proteolytic degradation.
It is activated by FXa or thrombin in FVIIIa which will complex with FIXa in the presence of phospholipids to activate FX in FXa.
A patient who is deficient in FVIII has hemophilia A.
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