CRYOcheck™ Platelet Lysate

Perfectly clean human platelet lysate stripped of other contaminating cells and proteins and prepared from platelets from healthy donors.
The concentration of platelets is adjusted to be equivalent to 250,000 to 300,000 platelets / µL, lysed and then frozen.

- No bovine additives
- No reconstitution error
- Ready to use in a few minutes after thawing (4 min at 37°C)
- Checked negative for all serology tests required by the FDA

Lupus anticoagulants (LA) are heterogeneous autoantibodies of the IgG and IgM type directly directed against a variety of anionic phospholipids such as cardiolipin, phosphatidylserine or phosphatidylinositol or against proteins having the capacity to bind to phospholipids such as β2-glycoprotein I (β2-GPI).

The presence of LA is primarily detected using sensitive in vitro tests using phospholipids, such as TCA (Activated Partial Time) or dRVVT. They have the in vitro capacity to prolong phospholipid-dependent clotting times but are most often associated with thrombotic complications in vivo (venous or arterial thrombosis, thrombocytopenia and fetal loss) and do not predispose to a risk of bleeding. DRVVT is routinely used in screening for LA. It is considered specific and robust.