TECHNOZYM® ADAMTS-13 Activity Cal Set
Freeze-dried
Packaging options
| 4-5450761 | Vial | 6 x 0.5 mL |
Calibration plasmas for the determination of ADAMTS-13 activity.
Description of the TECHNOZYM® ADAMTS-13 Activity Cal Set
A range of 6 additional calibrators for the TECHNOZYM® ADAMTS-13 Activity ELISA.
Informations
ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 13) is an enzyme (VWFcleaving protease or VWF-CP) that specifically cleaves von Willebrand factor (VWF), which induce platelet thrombus formation under high shear stress.
If the activity of ADAMTS13 is lowered for some reason, however, unusually large VWF multimers may accumulate, causing thrombosis due to platelet aggregation, which in turn may lead to TMA (thrombotic microangiopathy) such as TTP (thrombotic thrombocytopenic purpura).
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