Human Factor X
| 9-HCX-0050 | Vial | 100 µg |
| 9-HCX-0050-1 | Vial | 1 mg |
Origin : Human Blood / Plasma
Structure: 2 subunits (16 200 & 42 000), N-terminal Gla domain and 2 EGF domains
Description of the Human Factor X
Molecular Weight (Da) : 58 900
Extinction coef. : 11.6
Isoelectric point: 4.9-5.2
Buffer formulation : 50 % Glycerol / H₂O (v/v)
Advantages
The vast majority of zymogens is pure (without additives) with > 95 % purity SDS-PAGE.
No additive or preservative.
Informations
A proenzyme or zymogen is a protein precursor of an enzyme which can give, after activation, an active enzyme. Factor X (FX) is a glycoprotein synthesized by the liver, dependent on vitamin K. FX is involved in the common pathway of coagulation. It is activated in FXa by the FT-FVIIa complex or by the FVIIIa-FIXa complex in the presence of phospholipids. FXa is neutralized by TFPI and by antithrombin.
