Sheep polyclonal antibody anti-human protein S

Application : Immunoblotting, ELISA, RIEP
Host : Sheep
Molecular weight : 150 000
Extinction coefficient : 1.4
Immunogen: Purified human protein S
Buffer formulation : 50 % Glycerol / H₂O (v/v)

Custom needs by supplying you antibodies conjugated with biotin, HRP, FITC or other conjugates. Special formulations are available upon request. Discount according to quantities

Protein S is a vitamin K dependent protein. It is a physiological inhibitor of coagulation. It acts as a cofactor of activated protein C by promoting the inactivation of FVa and FVIIIa, prothrombin, of the prothrombinase complex, FX. A protein S deficiency can be either acquired (hepatocellular insufficiency, vitamin K deficiency, anti-protein S antibody, ...) or constitutional (heterozygous or homozygous deficiency) grouped into 2 types depending on whether the deficiency is quantitative (type I) or qualitative (type II).