FXIII Immunodepleted Deficient Human Plasma

Plasma frozen, immunodepleted, poor in platelets and certified to have less than 1% in FXIII.
It is deficient in both antigenic and functional assay.

- No bovine additives
- No reconstitution error
- No plasma alteration linked to freeze-drying
- Cryotubes ready to use after thawing (4 min at 37°C).

FXIII (FXIII) or fibrin stabilization factor is the zymogen of a transglutaminase. FXIII is activated by thrombin, it intervenes in the final phase of fibrinoformation to stabilize the fibrin clot. It is also involved in the phenomena of tissue repair and scarring by allowing the association of collagen and fibronectin.
There are constitutional deficits in FXIII which are autosomal recessive inheritance. The severe forms are associated with a hemorrhagic syndrome. Acquired FXIII deficiency due to anti-FXIII autoantibodies is also a very important cause of bleeding diathesis.
The consumption of FXIII in various diseases (malignant infections, Crohn's disease, Henoch-Schoenlein purpura, major surgery, ...) usually results from a moderate drop in the level of FXIII.