Human Native Factor VIII congenital Deficient Plasma
| 7-0800 | Kit | 5 x 1.0 mL |
Plasma from a single human donor with congenital Factor VIII deficiency.
Native coagulation factor deficient plasmas are fresh frozen plasmas obtained exclusively from donors with severe congenital clotting factor deficiency.
Description of the Human Native Factor VIII congenital Deficient Plasma
These native coagulation factor-deficient plasmas are recommended for the evaluation of the activity of coagulation factors by the method of assaying the level of prothrombin (PT) or activated partial thromboplastin time (TCA) requiring the use of a plasma lacking in factor (<1%) in hemostasis.
Advantages
- None of these plasmas contain inhibitors
- No additives or preservatives
- Freezing the plasmas makes it possible to keep the matrix perfectly intact and to avoid reconstitution.
- Packaging in plastic cryotubes suitable for all STA-R type micro-cup supports
Informations
Factor VIII is a glycoprotein mainly synthesized by the liver.
It circulates in the plasma in the form bound to VWF which protects it from rapid proteolytic degradation.
It is activated by FXa or thrombin in FVIIIa which will complex with FIXa in the presence of phospholipids to activate FX in FXa.
A patient who is deficient in FVIII has hemophilia A.
