Human protein S
| 9-HCPS-0090 | Vial | 100 µg |
| 9-HCPS-0090-1 | Vial | 1 mg |
Human protein S
Formulation : Glycérol 50% / H₂O (v/v)
Description of the Human protein S
MW(Da) : 69 000
Concentration : 6.1 mg/mL
Extinction coef. : 9.5
Isoelectric point : 5.0-5.5
Structure: single chain, Gla domain in NH2-terminal and 4 EGF domains
Advantages
The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities.
Discount according to quantities.
Informations
A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter. These proteins are often enzymes, and coFactors can be thought of as "helper molecules" aiding in biochemical transformations. Protein S is a 69 kDa-dependent vitamin K eglycoprotein synthesized by hepatocytes, endothelial cells, megakaryodytes and osteoblasts. It is a physiological inhibitor of coagulation.
Protein S acts as a cofactor of activated protein C by promoting the inactivation by proteaolysis of factors Va and VIIIa.
Protein S inhibits the activation of prothrombin and the formation of the prothrombinase complex on phospholipids as well as the activation of FX.
