Human Factor Va
| 9-HCVA-0110 | Vial | 50 µg |
| 9-HCVA-0110-1 | Vial | 1 mg |
Origin : Human Blood / Plasma
Formulation : 50 % Glycerol / 5 mM CaCl₂ (v/v)
Structure: 2 sub-units; heavy chain (94kDa) and light chain (74 kda)
Description of the Human Factor Va
1 900 to 4 600 units/mg
MW(Da) : 168 000
Coefficient d'extinction : 17.4
Determination of activity: coagulation test
Advantages
The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities.
Discount according to quantities.
Informations
A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter.
These proteins are often enzymes, and cofactors can be thought of as "helper molecules" aiding in biochemical transformations.
Factor V (FV) is a protein mainly synthesized by the liver. It is the enzymatic cofactor of FX and is activated in FVa by thrombin and / or FXa.
It forms with FXa a complex which, in the presence of phospholipids and calcium, activates prothrombin to thrombin.
The FVa is neutralized by the PCa.
