Human Factor V
| 9-HCV-0100 | Vial | 50 µg |
| 9-HCV-0100-1 | Vial | 1 mg |
Origin : Human Blood / Plasma
Buffer formulation : 50% Glycerol / H2O (v/v)
Description of the Human Factor V
29 to 84 units/mg
Molecular weight (Da) : 330 000
Extinction coef. : 9.6
Determination of activity: Factor V clotting assay
Structure: 1 subunit of 2196 amino acids
Advantages
The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities.
Discount according to quantities.
Informations
A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter.
These proteins are often enzymes, and cofactors can be thought of as "helper molecules" aiding in biochemical transformations. Factor V (FV) is a protein mainly synthesized by the liver.
It is the enzymatic cofactor of FX and is activated in FVa by thrombin and / or FXa. It forms with FXa a complex which, in the presence of phospholipids and calcium, activates prothrombin to thrombin.
The FVa is neutralized by the PCa.
