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IMUBIND® Vitronectin ELISA

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26-ADG803Kit96 tests tests

The IMUBIND® Vitronectin ELISA is an enzyme-linked immunosorbent assay for the quantitative determination of total Vitronectin in human plasma or serum or in any fluid where Vitronectin might be present.

Description of the IMUBIND® Vitronectin ELISA
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Vitronectin (Vn) is an adhesive glycoprotein, synthesized by the liver, released in plasma and present in the extracellular matrix. Vn binds PAI-1.
This complex fully activates PAI-1, unlike PAI-1 in solution, where it does not appear to be stable and inactive.
Vn therefore seems to regulate the enzymatic specificity of PAI-1, by stabilizing it. Decreased Vn levels occur in DICs and liver disease (cirrhosis). Vn deposition is associated with atherosclerotic lesions.

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