pNAPEP-8703
| 61038703 | Vial | 1 x 25 mg |
Specific synthetic chromogenic substrate for the measurement of the C1-esterase activity in plasma, used for the determination of C1 INH : equivalent Pefachrome® C1E.
The chromogenic peptides are also used in quality control of pharmaceutical and other preparations.
As we are manufacturer, we can supply you from milligram to gram.
Description of the pNAPEP-8703
Peptide sequence : CH₃CO-Lys(Cbo)-Gly-Arg-pNA, AcOH
Chemical structure : C₃₂H₄₅N₉O₁₀, AcOH
Chemical name : Methylcarbonyl-lysyl(ε-benzyloxycarbonyl)-glycyl-arginine-paranitroaniline monoacetate
Molecular Weight : With AcOH = 715,8 g/mol - without AcOH = 655,7 g/mol
Km : 23.1 µM
pNA free ≤ 0.5 %
Purity grade ≥ 95 %
Advantages
Package Inserts, certificate of analysis supplied.
Material safety Data Sheet (MSDS) supplied.
Prolonged stability following reconstitution (> 3 months).
Discount according to quantities.
Informations
Over 20 years of expertise as manufacturer of the pNAPEP® line of chromogenic peptide substrates.
This is a line of high quality substrates, which allow testing of serine proteinases.
Their focus is on enzymes involved in coagulation and fibrinolysis for thrombin, Factor Xa, Factor XIIa, kallikrein, activated protein C, plasmin and plasminogen-SK.
Our chromogenic substrates pNAPEP are equivalent to the brand name CHROMOGENIX, WERFEN, PENTAPHARM DSM or DIAGNOSTICA STAGO.
These are synthetic peptides that react with proteolytic enzymes under formation of colour which can be followed spectrophotometrically and the intensity of which is proportional to the proteolytic activity of the enzyme.
C1 INH is a regulatory protein that acts as an inhibitor of various serine proteases in the complement system, the kallikrein-kinin system, the coagulation cascade and in fibrinolysis.
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