Human kallikrein
Liquid
Packaging options
11-473 | Vial | 1 mg |
Structure : 52 kDa heavy chain and a 33 kDa light chain linked by disulfide bridges.
Formulation : 1mg in a buffer composed of 4mM sodium acetate / hydrochloride, 150mM NaCl, pH 5.3
Description of the Human kallikrein
MW(Da) : 85 000
Coef. Extinction : 1.17
Informations
Kallikrein is a glycoprotein derived from prekallikrein. It is non-covalently complexed to the high molecular weight kininogen. FXIIa activates the transformation of prekallikrein into kallikrein which will activate FXII and hydrolyze KHPM into several fragments. In fibrinolysis, kallikrein is also able to activate pro-urokinase to urokinase.






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