Relipidated recombinant human tissue Factor protein
Freeze-dried
Packaging options
| 11-4500L/B | Vial | 250 ng |
Formulation: 50mM tris buffer, 100mM NaCl, pH 7.6 and 200 mg / mL of trehalose.
Description of the Relipidated recombinant human tissue Factor protein
Structure: The protein contains amino acids 1 to 263 including the extracellular, transmembrane and cytoplasmic domains.
MW(Da) : 45 000
Advantages
The lyophilized presentation allows greater stability until the expiration date.
Informations
Tissue factor (FT) is a transmembrane glycoprotein which is primarily responsible for activating coagulation cascades in the event of a vascular breach. The binding of FVII to its receptor, expressed by the cells of the subendothelium exposed by the lesion, allows its very rapid activation by traces of FXa, circulating in trace amounts in vivo. The FT-FVIIa complex then causes the activation of FIX and FX and the formation of thrombin.
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