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Bovine Factor Va

Frozen
Packaging options
9-BCVA-1110Vial100 µg
9-BCVA-1110-1Vial1 mg

Formulation : 50/50 (v/v) glycérol/H₂O, 5 mM CaCl₂

Description of the Bovine Factor Va

1 500 to 4 600 units/mg
MW(Da) : 168 000
Extinction coef. : 17.4
Determination of activity: coagulation test
Structure: 2 sub-units; heavy chain (94kDa) and light chain (74 kda)

Advantages

The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery
Delivery in large quantities
Discount according to quantities

Informations

A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter.
These proteins are often enzymes, and cofactors can be thought of as "helper molecules" aiding in biochemical transformations.
Factor V (FV) is a protein mainly synthesized by the liver. It is the enzymatic cofactor of FX and is activated in FVa by thrombin and / or FXa.
It forms with FXa a complex which, in the presence of phospholipids and calcium, activates prothrombin to thrombin. The FVa is neutralized by the PCa.

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