Murine monoclonal antibody against human FVIIa IgG

Application: Inhibitor of the activity of FVIIa, Immunoblotting (in non-reduced condition)
Host : Mouse
Immunogen : Human purified FVIIa

The lyophilized presentation allows greater stability until the expiration date.

Factor VII (FVII) is a glycoprotein synthesized by the liver, zymogen of a serine protease. It is a vitamin K dependent factor belonging to the prothrombin complex. Its half-life is 4 to 6 hours and it is the only coagulation factor present in trace amounts in its active form. When tissue factor appears on the endothelial surface, activated FVII associates with it initiating the extrinsic pathway for coagulation. This complex (FT-FVIIa) will activate the FX in FXa and the FIX in FIXa.