TECHNOSCREEN® ADAMTS13 Activity
4-5700100 | Kit | 10 tests |
The TECHNOSCREEN® ADAMTS-13 Unit Test is a semi-quantitative system for the determination of ADAMTS-13 protease activity in citrated human plasma.
Description of the TECHNOSCREEN® ADAMTS13 Activity
This test was designed to be used as a first-line test to quickly estimate ADAMTS-13 activity.
Informations
ADAMTS-13 is an enzyme responsible for the cleavage of von Willebrand factor under blood flow conditions.
A functional defect in the activity of this enzyme leads to the presence of high molecular weight isoforms of vWF, and thus leads to increased platelet aggregation mainly in areas of microvascularization.
This is the known major cause of Thrombotic Thrombocytopenic Purpura (TTP).





