Factor XII Deficient Plasma Native
Freeze-dried
Packaging options
| 4-5194008 | Vial | 5 x 1.0 mL | 100 tests |
Plasma deficient for Factor XII assay.
Description of the Factor XII Deficient Plasma Native
Native Factor XII Deficient Plasma is a pool of donor plasmas deficient in FXII, native (congenital deficiency), lyophilized, with a coagulant activity <3% for FXII.
Informations
Factor XII (FXII) is a glycoprotein synthesized by the liver. FXII participates in the contact phase which initiates the intrinsic pathway of coagulation.
Activated on contact with a negatively charged surface, it becomes capable of activating prekallikrein and kallikrein (amplified by KHPM) then FXI to FXIa in the presence of KHPM.
The FXIa thus formed activates the FXII in FXIIa, amplifying the reaction.
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